M E D I A and A N I M A T I O N

Clicking on the following links will launch either a Shockwave or Flash Player in this frame. If your browser is not equipped to play these files, go to the Macromedia web site to download the appropriate players.

Theory:
Evolution of the Mitochondrial Genome
Polymerase Chain Reaction
Cycle Sequencing

Problems:
Solving the Mystery of the Neandertals
Solving the Mystery of the
Romanovs

Video:

The following video clips are from an interview with Dr. Svante Pääbo, Director of the Department of Evolutionary Genetics, Max Planck Institute. Select the clip will launch the RealPlayer in a separate window. If your browser is not equipped for RealPlayer content, go to the Real web site to download the free RealPlayer.

Clip 1: 1 minute 27 seconds
What is the age limit of DNA?

Clip 2: 45 seconds
What contributes to DNA degradation?

Clip 3: 1 minute 15 seconds
How to pick the best sample from which to isolate DNA.

Clip 4:
1 minute 12 seconds
Problems with getting "true" ancient DNA.

Clip 5:
50 seconds
How he ended up working with ancient DNA.

Clip 6:
41 seconds
The inheritance of accumlated mutations.

Clip 7:
29 seconds
Why it was relatively easier to reconstruct mitochondrial DNA sequences.

Clip 8:
1 minute 8 seconds
The Neandertal question: are they related to modern humans or not?

Clip 9:
40 seconds
What molecular genetics tells us about the Neandertal relationship to modern humans.

Clip 10:
59 seconds
Other possible ancient DNA results.



M I T O C H O N D R I A L  C O N T R O L  R E G I O N

DNA Learning Center, Cold Spring Harbor Laboratory
Noncommercial, educational use only.